Medscape articles:
From: AIDS Reader
Where Now for Trizivir? - Role of the Triple-NRTI Pill Post-ACTG 5095 - Graeme J. Moyle, MD, MBBS
Triple NRTI therapy should be avoided as sole initial therapy.
Histoplasmosis in a patient with AIDS
Long-term complications of nucleoside reverse transcriptase inhibitor therapy - Douglas Dieterich MD
Review of the major long-term complications associated with NRTIs: hyperlactatemia and lactic acidosis/hepatic steatosis, other hepatotoxicities, pancreatitis, lipodystrophy/lipoatrophy, neuropathy, and haematologic toxicities.
From: American Journal of Clinical Pathology
Toxic effects of nucleoside reverse transcriptase inhibitors on the liver
The authors demonstrate that NRTI-induced toxic effects in the liver may occur as indolent nonspecific disease with variable histologic features and emphasises the diagnostic value of electron microscopy, particularly when diffuse steatosis is absent.
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HIV Treatment Bulletin Vol 4 No 6 July 2003
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